Azo-polymeric films represent the perfect candidates for cell cultures. Polysiloxanes and linear poly (p-chloromethyl) phenylethylene with azobenzene unit connected to the lateral chains were synthesized and characterised. Thanks to the presence of photo-responsive azobenzene moieties, the films of those polymers showed totally different responses underneath lightweight ultraviolet illumination|UV|actinic radiation actinic ray} light by matter reorganization at the nano level. A surface relief grating was obtained underneath controlled lightweight irradiation. The SRG method is very complicated and depends on a spread of things. The nanostructure azopolymeric films (deposed on glass or olymethylmethacrylate surfaces) ar appropriate for cell culture applications. The cell response has been evaluated varied} azopolymers having various film thicknesses and topographies. The film physical property is influenced by the chemical structure of the most compound chain, whereas the adhesion properties are adjusted by the sort of grafted azo-phenol. The surface relief, elasticity, and adhesion properties management the bio-cultures development. Within the past twenty years, we’ve got witnessed important progress in developing high performance stimuli-responsive compound materials. This review focuses on recent developments within the preparation and application of tabby stimuli-responsive polymers, together with thermo responsive layers, pH/ionic-responsive hydro gels, photo-responsive film, magneticallyresponsive composites, electro active composites, and solvent-responsive composites. Several necessary new applications for stimuli-responsive polymers belong to the sector of nano- and micro-fabrication, wherever stimuli-responsive polymers ar being established as necessary manipulation tools. Some techniques are developed to by selection position organic molecules then to get well-defined tabby substrates at the micrometer or sub micrometer scale. Ways for patterning of stimuli-responsive hydro gels, together with lithography, beam lithography, scanning probe writing, and printing techniques (microcontact printing, matrix printer printing) were surveyed. we tend to additionally surveyed the applications of nanostructure stimuli-responsive hydro gels, like biotechnology (biological interfaces and purification of biomacromoles), switchable wettability, sensors (optical sensors, biosensors, chemical sensors), and actuators. The leaves of action plant collapse suddenly once touched, and people of the Venus trap snap shut on doomed insect prey; the leaflets of Desmodium gyrans rotate, and sunflowers flip toward the sun; and chameleons amendment color in line with their atmosphere. At their most elementary level, several of the foremost necessary substances in living systems are macromolecules with structures and behaviors that modify in line with the conditions within the encompassing atmosphere. Mimicking the functions of such organisms, scientists have created nice efforts to synthesize stimuli-responsive polymers that have significance to science and promising applications. Incorporating multiple copies of purposeful teams that ar without delay amenable to an amendment in character (e.g., charge, polarity, and solvency) on a compound backbone causes comparatively minor changes in chemical structure to be synergistically amplified to motivate dramatic transformations in gross material properties. Polymers like proteins, polysaccharides, and nucleic acids ar gift as basic elements in living organic systems. Artificial polymers, that are designed to mimic these biopolymers, are developed into a spread of purposeful forms to fulfill industrial and scientific applications. These artificial polymers are classified into totally different classes supported their chemical properties. Bound special forms of polymers have emerged as terribly helpful category of polymers having their own special chemical properties and applications in numerous areas. These “stimuli-responsive” polymers (SRPs) are diversely known as stimuli-sensitive, intelligent, smart, or environmentally-sensitive polymers. SRPs will quickly change with relevancy configuration or dimension underneath the influence of stimuli like temperature, pH value, light, flux, electricity, and solvent/water. These polymers may have totally different compositions and design, together with not solely homopolymers however additionally statistical/block copolymers, graft copolymers, and molecular brushes. They will be additionally grafted on/from surfaces or be used as with chemicals or physically cross-linked gels. SRPs are sometimes capable of stimuli-induced conformational changes, reversible solubility management, and reversible self-assembly into compound micelles or vesicles. Given these distinctive properties, stimuli-responsive polymers are being developed to be used in such fields as drug delivery, cell adhesion, sensors, and mechanism systems, emotional of encapsulated materials and trafficking of molecules through compound membranes
