Osteopathy is a holistic healthcare approach that focuses on the diagnosis, treatment, and prevention of musculoskeletal disorders. It encompasses a range of manual techniques aimed at restoring balance and promoting overall well-being. This comprehensive review explores the principles underlying osteopathy, delves into various treatment techniques employed by osteopaths, and examines the existing evidence supporting its efficacy in managing musculoskeletal conditions. By shedding light on the principles and practices of osteopathy, this review aims to provide a thorough understanding of this alternative therapeutic modality.