Gene medical aid is that the delivery of a therapeutic factor for endogenous cellular expression with the goal of rescuing a sickness composition. it's been accustomed treat associate degree increasing range of human diseases with several ways proving safe and efficacious in clinical trials. Factor delivery could also be infective agent or non-viral, performed in vivo or ex vivo, and depends on factor integration or transient expression; all of those techniques are applied to the treatment of Fabric sickness. Fabric sickness could be a genetic abnormality of the αgalactosidase a factor