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Type of magnesium salt and formulation solubility determines bioavailability of magnesium food supplements

An-Katrien Vynckier

Magnesium (Mg2+), an essential mineral and cofactor of more than 300 enzymatic processes, has a regulating role in energy metabolism, protein synthesis, muscle and nerve function, blood glucose and blood pressure control.(1) EFSA proposes an Adequate Intake of 350 and 300 mg/day for men and women, respectively.(2) Given deficiencies present in over 50% of the normal population, magnesium is currently a popular nutritional supplement.(3) Based on the source of elemental magnesium, the supplements currently available on the market can be divided into 2 different categories: inorganic or organic salts of magnesium. Inorganic magnesium compounds are generally perceived as not as easily absorbable as organic magnesium compounds.


 
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