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Instrucciones para los autores

Revista de bioquímica clínica, una revista internacional impresa y en línea de acceso abierto en inglés, considerará para su publicación artículos originales, comunicaciones breves, informes de casos, cartas al editor, editoriales y minirreseñas. Se da énfasis a todos los aspectos de la bioquímica clínica. Las presentaciones serán evaluadas según su validez y mérito científico. Los manuscritos se reciben en el entendido de que se envían únicamente a la Revista de bioquímica clínica y que ninguno de los materiales contenidos en el manuscrito ha sido publicado previamente ni está bajo consideración para publicación en otro lugar, excluyendo los resúmenes. La Revista se adhiere a la Licencia Creative Commons “Atribución − No Comercial − CC BY-NC” para todos los envíos de ACCESO ABIERTO. El editor se reserva los derechos de autor comerciales de todo el material publicado, y permite la reproducción y el uso de copias individuales en cualquier medio siempre que la obra esté debidamente citada. Para obtener permiso para reproducir y distribuir múltiples copias de la publicación, comuníquese con el editor encontacto@pulsus.com . Las declaraciones y opiniones son responsabilidad de los autores.


Los autores pueden enviar su manuscrito como archivo adjunto de correo electrónico a biochem@clinicalmedicaljournals.com


Cargos por página : No se aceptarán copias impresas de manuscritos. Toda la comunicación se realizará electrónicamente. Para garantizar que la versión final publicada coincida con el archivo electrónico, asegúrese de utilizar únicamente las siguientes fuentes: Arial, Courier, Symbol y Times. El uso de fuentes no estándar puede provocar que falten símbolos. El tamaño de la fuente no debe ser menor de 7 puntos ni mayor de 14 puntos. El envío de manuscritos para la Revista de bioquímica clínica se cobrará $500 como cargo básico de procesamiento del artículo, si se acepta para publicación.


GENERAL INSTRUCTIONS: Arrange the manuscript as follows: Title page, structured Abstract and Key words, Introduction, Methods, Results, Discussion, Acknowledgements, Sources of Funding, Disclosures, References, Figure legends, Tables and Figures. Do not import figures into the text file. Number the pages consecutively, beginning with the title page as 1. The last name of the first author should be typed at the top of each page. To ensure that the final, published version matches the electronic file, make sure that you use only Times New Roman or Arial, fonts, double spaced. The use of nonstandard fonts may lead to missing symbols. Text files must be saved as doc.files. All manuscripts must be accompanied by a covering letter detailing what is being submitted and indicating the author to whom we should address correspondence and page proofs. Author must sign a publishing agreement supplied by Grupo Pulso. upon acceptance for publication.
The editors encourage authors to provide the names (including e-mail address) of at least five potential reviewers who have not been collaborators or coauthors within the past three years and have not provided advice or critique of the submitted manuscript. Authors may list up to a maximum of three reviewers they wish to exclude.
TITLE PAGE: The title, authors’ names (including full first or middle names and credentials [MD, PhD, MSc, etc]) and a short running title of 45 characters should appear on the title page. Include the name of the institution from which the work originated plus the full name, mailing address with postal code, telephone and fax numbers and e-mail address of the author to whom communication, proofs and requests for reprints should be sent.
ABSTRACT AND KEY WORDS: On a separate page, provide a structured abstract of no more than 250 words. It should be subdivided into four subsections headed: Objectives, Methods, Results and Conclusions. Abstract for case reports need not to be structured but are limited to 150 words. Abbreviate only standard units of measurement. At the end of the abstract, include a list of three to six key words or phrases for indexing purposes.
TEXT: Text should be divided into Introduction, Methods, Results and Discussion. Appropriate subheadings should be provided in the Methods, Results and Discussion sections. Abbreviations should follow the form recommended in ‘Uniform Requirements for Manuscripts Submitted to Biomedical Journals’ prepared by the International Committee of Medical Journal Editors and published in Ann Intern Med 1997;126:36-47 and Can Med Assoc J 1997;156:270-7.
Create a list of nonstandard abbreviations and nonstandard acronyms used in the text. References, figures and tables should be cited in the text with numbers assigned according to the order of mention in the text.
ACKNOWLEDGEMENTS: Brief acknowledgements may appear at the end of the text, before the references.
REFERENCES: References should be cited in numerical order in which they appear in the text. Identify references in the text by Arabic numerals in parentheses on the line. Personal communications, manuscripts in preparation and other unpublished data are not cited in the reference list but may be mentioned in the text in parentheses. References cited in figures and tables, but not in the text, should also be numbered. Type the reference list double-spaced, separate from the text. The style and punctuation of references is as follows:


List all authors if 6 or fewer; otherwise, list first 3 and add ‘et al’. Do not use periods after authors’ initials.
1. Kohl P, Day K, Noble D, et al. Cellular mechanisms of cardiac mechano-electric feedback in a mathematical model. Can J Cardiol 1998;14:111-9.


2. Svensson LG, Crawford ES. Cardiovascular and Vascular Disease of the Aorta. Toronto: WB Saunders Company, 1997:184-5.

Chapter in book:

3. Trehan S, Anderson JL. Thrombolytic therapy. In: Yusuf S, Cairns JA, eds. Evidence Based Cardiology. London: BMJ Books, 1998:419-44.

Web sites:

4. National Library of Medicine. Images from the History of Medicine. (Accessed January 5, 1999).
FIGURES: All figures must be submitted in their original formats. The lettering, decimals, lines and other details on the figures should be sufficiently large to withstand reduction and reproduction. Graphs must be created using Microsoft Word (.doc), Microsoft Power Point (.ppt), Microsoft Excel (.xls), Corel Draw (.cdr), or adobe illustrator (.al or .eps). Any graphics imported into your figure must also be submitted separately. Photographs may be scanned at a resolution of no less than 300 dpi and saved as a .tiff file. Place crop marks on photomicrographs to show the essential field, and designate special features with arrows (which must contrast with the background).
FIGURE LEGENDS: Type double-spaced, separate from the rest of the text with figure numbers corresponding to the order in which figures are presented in the text. Identify all abbreviations appearing on figures in alphabetical order at the end of each legend. Enough information should be given to allow interpretation of the figure without reference to the text. Figure legends should not appear on the actual figures. Written permission from the publisher and author to reproduce any previously published figures must be included.
TABLES: Type double-spaced, on a separate page of the rest of the text, with the number above the table and explanatory notes below. Table numbers should appear in Arabic numerals and should correspond to the order of the tables in the text. If abbreviations are used an alphabetical listing must be included in the footnote. Written permission from publisher to reproduce any previously published tables must be included.
POLICY ISSUES: All statements and opinions are the responsibility of the authors. With submission of the manuscript, a letter of transmittal must indicate that all authors have participated in the research, and have reviewed and agree with the content of the article.
CONFLICT OF INTEREST: All authors must disclose any commercial associations or other arrangements (eg, financial compensation received, patient-licensing arrangements, potential to profit, consultancy, stock ownership, etc) that may pose a conflict of interest in connection with the article. This information will be made available to the editor and reviewers, and may be included as a footnote at the editor’s discretion.
ETHICS OF HUMAN AND ANIMAL EXPERIMENTS: If human subjects are involved, the text must indicate that all gave informed consent and that the protocol was approved by the institutional review committee. If experimental animals are used, provide a statement in the text to indicate that all procedures followed were in accordance with institutional policies.
PRUEBAS: Los autores deben conservar una copia de sus manuscritos originales ya que se les enviarán pruebas de página sin el manuscrito original. Para evitar retrasos en la publicación, los autores deben devolver las pruebas dentro de las 48 horas siguientes por fax o correo electrónico.




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